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FUSARIC ACID
Descriptors Found:
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DeCS
Descriptor
English
:
Fusaric Acid
Descriptor
Spanish
:
Ácido Fusárico
Descriptor
Portuguese
:
Ácido Fusárico
Tree Number:
D03.066.707.200
D03.383.725.705.200
Definition
English
:
A picolinic acid derivative isolated from various
Fusarium
species. It has been proposed for a variety of therapeutic applications but is primarily used as a
research
tool. Its mechanisms of action are poorly understood. It probably inhibits
DOPAMINE BETA-HYDROXYLASE
, the enzyme that converts
dopamine
to
norepinephrine
. It may also have other actions, including the inhibition of
cell proliferation
and DNA synthesis.
Indexing Annotation
English
:
/biosyn permitted if by organism
Pharmacological Action:
Dopamine Agents
Enzyme Inhibitors
Nucleic Acid Synthesis Inhibitors
History Note
English
:
91(75); was see under PICOLINIC ACIDS 1975-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
24003
Unique Identifier:
D005669
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS